Perrin C White Selected Research

galactose-6-phosphate dehydrogenase

1/2018	Alterations of Cortisol Metabolism in Human Disorders.
8/2008	Physiological roles of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase.
3/2008	Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy.
3/2006	Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation.
10/2005	Genotypes at 11beta-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample.
6/2005	Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.
8/2003	Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency.

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Perrin C White Research Topics

Disease

13	Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal) 12/2022 - 06/2002
9	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2018 - 09/2007
8	Insulin Resistance 10/2015 - 10/2005
6	Type 2 Diabetes Mellitus (MODY) 01/2018 - 08/2008
6	Cortisone reductase deficiency 01/2018 - 08/2003
6	Adenoma (Adenomas) 03/2006 - 11/2002
4	Hypertension (High Blood Pressure) 01/2018 - 11/2004
4	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 01/2018 - 06/2002
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 03/2006
3	Obesity 01/2018 - 08/2008
3	Neoplasms (Cancer) 01/2013 - 02/2003
3	Hyperglycemia 06/2012 - 03/2004
3	Cushing Syndrome 09/2010 - 02/2003
2	Hyperandrogenism 01/2018 - 02/2007
2	Graves Disease (Basedow Disease) 01/2018 - 10/2016
2	Weight Gain 01/2018 - 10/2012
2	Disorders of Sex Development (Intersexuality) 10/2012 - 06/2002
2	Hypovolemia 10/2012 - 03/2004
2	Muscular Diseases (Myopathy) 01/2010 - 03/2008
2	Adrenal Insufficiency (Adrenal Gland Hypofunction) 10/2007 - 06/2002
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 10/2005 - 08/2003
1	Gender Dysphoria 10/2019
1	And Genital Anomalies Adrenal Hypoplasia Congenita Metaphyseal Dysplasia Intrauterine Growth Retardation 12/2018
1	Body Odor 12/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Adrenal Rest Tumor 01/2018
1	Wasting Syndrome (Wasting Disease) 05/2017
1	Gambling (Pathological Gambling) 01/2017
1	Neutropenia 10/2016
1	Arthralgia (Joint Pain) 10/2016
1	Exophthalmos (Proptosis) 10/2016
1	Exanthema (Rash) 10/2016
1	Dwarfism 02/2015
1	Essential Hypertension 07/2013
1	Glucose Intolerance 01/2013
1	Failure to Thrive 10/2012
1	Shock 10/2012
1	Inflammation (Inflammations) 06/2012
1	Hypocalcemia 06/2012
1	Vitamin D Deficiency 01/2012
1	Overweight 01/2012
1	Infections 05/2010
1	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 02/2010
1	Epilepsy (Aura) 01/2010
1	Deafness (Deaf Mutism) 01/2010

Drug/Important Bio-Agent (IBA)

13	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2022 - 06/2002
7	Steroid 21-Hydroxylase (21 Hydroxylase)IBA 01/2019 - 03/2004
7	AndrogensIBA 12/2018 - 06/2002
7	galactose-6-phosphate dehydrogenaseIBA 01/2018 - 08/2003
7	AldosteroneIBA 10/2015 - 03/2004
6	GlucocorticoidsIBA 01/2022 - 02/2003
5	Glucose (Dextrose)FDA LinkGeneric 10/2015 - 03/2008
5	Insulin (Novolin)FDA Link 01/2012 - 12/2005
5	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 03/2006 - 03/2004
4	SaltsIBA 05/2017 - 06/2002
4	11-beta-Hydroxysteroid Dehydrogenase Type 1IBA 08/2008 - 08/2003
4	Cortisone FDA Link 02/2007 - 02/2003
3	MineralocorticoidsIBA 01/2018 - 10/2012
3	EnzymesIBA 01/2018 - 06/2005
3	SteroidsIBA 02/2014 - 06/2002
3	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2010 - 03/2006
3	CorticosteroneIBA 03/2008 - 03/2004
2	Gonadal Steroid Hormones (Sex Hormones)IBA 10/2019 - 10/2012
2	Pharmaceutical PreparationsIBA 01/2018 - 08/2008
2	ReninIBA 01/2018 - 07/2013
2	SodiumIBA 07/2013 - 06/2005
2	Proteins (Proteins, Gene)FDA Link 01/2013 - 01/2010
2	CalciumIBA 06/2012 - 01/2010
2	Hemoglobins (Hemoglobin)IBA 01/2012 - 10/2011
2	11-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)IBA 10/2005 - 02/2003
2	11-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA 02/2003 - 11/2002
1	DNA Polymerase IIIBA 12/2018
1	IodineIBA 01/2018
1	NADP (NADPH)IBA 01/2018
1	rilonacept FDA Link 01/2018
1	AntibodiesIBA 10/2016
1	Thyroid-Stimulating ImmunoglobulinsIBA 10/2016
1	Methimazole (Thiamazole)FDA LinkGeneric 10/2016
1	Transaminases (Aminotransferases)IBA 10/2016
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 02/2015
1	Transcription Factors (Transcription Factor)IBA 01/2013
1	FludrocortisoneIBA 10/2012
1	Vitamin D FDA LinkGeneric 06/2012
1	Toll-Like Receptors (Toll-Like Receptor)IBA 06/2012
1	InflammasomesIBA 06/2012
1	Fatty Acids (Saturated Fatty Acids)IBA 06/2012
1	25-hydroxyvitamin DIBA 01/2012
1	hydroxide ionIBA 01/2012
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 11/2011
1	Dipeptidyl-Peptidase IV InhibitorsIBA 05/2010
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 05/2010
1	Sitagliptin Phosphate (Januvia)FDA Link 05/2010
1	Growth Hormone (Somatotropin)IBA 04/2010
1	Arginine Vasopressin (Argipressin)IBA 02/2010
1	Neurophysins (Neurophysin I)IBA 02/2010

Therapy/Procedure

8	Therapeutics 01/2018 - 09/2007
5	Glycemic Control 11/2018 - 04/2009
1	Thyroidectomy 01/2018
1	Aftercare (After-Treatment) 01/2018
1	Injections 02/2015